| Ubaid Period | 5000-4000 |
| | Tell Hamoukar (urban center, N. Mesopotamia) |
| Proto-Literate Period | 4000-2900 |
| |
| | trade contacts with N. Mesopotamia, Syria, Arabia |
| | |
| | colonization of N. Mesopotamia |
| | invention of writing (Uruk) |
| | initial trade contacts with Egypt |
| |
| Early Dynastic Period | 2900-2334 |
|
| |
| Akkadian Empire | 2334-2154 |
|
| |
| Guti Interregnum | 2154-2112 |
| |
| |
| |
| Third Dynasty of Ur | 2112-2004 |
|
| 2004 |
| |
| Isin-Larsa Period | 2025-1887 |
Dynasty of Larsa (Amorite) | 2025-1863 |
Dynasty of Isin (Sumero-Akkadian) | 2017-1887 |
| |
| Old Assyria | 2025-1365 |
| 2025 |
| 1753 |
| 1715 |
| 1500-1365 |
| |
| Old Babylonian Period | 1994-1595 |
Babylon Dynasty 1: Amorite | |
| 1792-1750 |
| 1753 |
| 1595 |
| |
| Dynasty of the Sea-Land | 1700-1570 |
| |
| Middle Babylonia | 1570-689 |
| 1570-1225 |
| 1225-1186 |
| 1186-1157 |
| 1157-1156 |
| 1156-689 |
| |
| Middle Assyria | 1365-883 |
| 1274 |
| 1225-1186 |
| |
| Neo-Assyria | 883-609 |
| 689-625 |
| 671-663 |
fall of Nineveh (Chaldeans) | 609 |
| |
| Neo-Babylonia | 625-539 |
|
| 609-539 |
| 539 |
| |
| Persian Empire | 547-331 |
|
| 547 |
| 546-478 |
| 539 |
| 525-404 |
| 492 |
sack of Babylon (Persians) | 482 |
| 499-490 |
| 480-479 |
| 478 |
| 401 |
| 343-332 |
| 334 |
| 332 |
fall of Babylon (Macedonians) | 331 |
| |
| Macedonian Empire | 334-305 |
| 334-323 |
| 323-305 |
| |
| Seleucid Kingdom | 305-63 |
fall of Babylon (Parthians) | 126 |
| 63 |